DNA-dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes, bioRxiv, 2023.09.15.557979

Redox-dependent condensation and cytoplasmic granulation by human ssDNA binding protein 1 delineate roles in oxidative stress response, bioRxiv, 2023.07.25.550517

Bloom syndrome helicase contributes to germ line development and longevity in zebrafish, Cell Death and Disease, 13:363 (2022)

The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops, Nature Communications,13, Article number: 654 (2022)

Evaluation and modulation of DNA lesion bypass in an SV40 large T antigen-based in vitro replication system, FEBS Open Bio,11: 1054-1075. (2021)

Improved inhibitory and ADMET properties of blebbistatin derivatives indicate that blebbistatin scaffold is ideal for drug development targeting myosin-2., J Pharm Exp Ther,376: 358-373. (2020)

Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness, Cell ,Volume 183, Issue 2, Pages 335-346.e13 (2020)

Phase separation by ssDNA binding protein controlled via protein−protein and protein−DNA interactions, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA ,117 (42) 26206-26217. (2020)

Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion, SCIENTIFIC REPORTS,10 : 1 Paper: 13341 (2020)

Mgs1 protein supports genome stability via recognition of G-quadruplex DNA structures, FASEB JOURNAL ,34 : 9 pp. 12646-12662. , 17 p. (2020)

Homology sensing via non-linear amplification of sequence dependent pausing by RecQ helicase, eLife,29;8. pii: e45909 (2019)

Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation, SCIENTIFIC REPORTS,9 Paper: 4825 (2019)

Targeting myosin by blebbistatin derivatives: Optimization and pharmacological potential, Trends Biochem Sci,43(9):700-713 (2018)

Live cell superresolution-SIM imaging analysis of the intercellular transport of microvesicles and costimulatory proteins via nanotubes between immune cells, Methods Appl Fluoresc,6(4):045005 (2018)PDF

Functional fine-tuning between bacterial DNA recombination initiation and quality control systems, PLoS ONE, 13(2), e0192483 (2018)

Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state, Nucleic Acids Res, 46(8):3967-3980. (2018)

Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination, Proc Natl Acad Sci USA, 114: E466-E475. (2017)PDF

Unrevealed part of myosin’s powerstroke accounts for high efficiency of muscle contraction, Biochim Biophys Acta, 1861(9):2325-2333. (2017)

Structural insight into a partially unfolded state preceding aggregation in an intracellular lipid-binding protein, FEBS J, 284(21):3637-3661. (2017)

RecQ helicase triggers a binding mode change in the SSB-DNA complex to efficiently initiate DNA unwinding, Nucleic Acids Res, 45(20):11878-11890. (2017)

Structural basis of Ribosomal S6 Kinase 1 (RSK1) inhibition by S100B Protein: modulation of the Extracellular Signal-regulated Kinase (ERK) signaling cascade in a calcium-dependent way., J Biol Chem,291 : 1 pp. 11-27. , 17 p. (2016)PDF

Recent adaptations of fluorescence techniques for the determination of mechanistic parameters of helicases and translocases, Methods, 108, 24-39 (2016)

The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling, Sci Rep,5 Paper: 11091 , 13 p. (2015)PDF

A Nucleotide- and HRDC-domain-dependent Structural Transition in DNA-bound RecQ Helicase., J Biol Chem,289 : 9 pp. 5938-5949. , 12 p. (2014)PDF

Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations, Nucleic Acids Res,43 : 2 pp. 1090-1097. , 8 p. (2015)PDF

A subdomain interaction at the base of the lever allosterically tunes the mechanochemical mechanism of Myosin 5a., PLOS ONE ,8 : 5 p. e62640 (2013)PDF

From keys to bulldozers: expanding roles for winged helix domains in nucleic acid-binding proteins, Trends Biochem Sci,38 pp. 364-371. , 8 p. (2013)

Visualization of human Bloom’s syndrome helicase molecules bound to homologous recombination intermediates, FASEB J,27 : 12 pp. 4954-4964. , 11 p. (2013)

Overdamped mechanical model of myosin II, Period Polytech Civ Eng , 57 : 1 pp. 11-19. , 9 p. (2013)

Myosin and tropomyosin stabilize the conformation of formin-nucleated actin filaments, J Biol Chem,287 : 38 pp. 31894-31904. , 11 p. (2012)PDF

Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis, Proc Natl Acad Sci U S A.,109 : 12 pp. 4509-4514. , 6 p. (2012)PDF

A single mutation in a tunnel to the active site changes the mechanism and kinetics of product release in haloalkane dehalogenase LinB, J Biol Chem,287 pp. 29062-29074. , 13 p. (2012)PDF

Azidoblebbistatin, a photoreactive myosin inhibitor, Proc Natl Acad Sci U S A,109 : 24 pp. 9402-9407. , 6 p. (2012)

RecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical coupling, Proc Natl Acad Sci U S A. ,109 : 25 pp. 9804-9809. , 6 p. (2012)PDF

Complex activities of the human Bloom’s syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains., Nucleic Acids Res,40 : 9 pp. 3952-3963. , 12 p. (2012)PDF

Myosin cleft closure determines the energetics of the actomyosin interaction, FASEB J.,25 : 1 pp. 111-121. , 11 p. (2011)

Switch 1 mutation S217A converts myosin V into a low duty ratio motor, J Biol Chem,23 : 284 pp. 2138-2149. , 12 p. (2009)PDF

Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke, Proc Natl Acad Sci U S A,107 : 15 pp. 6799-6804. , 6 p. (2010)PDF

Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms, J Biol Chem,285 : 49 pp. 38649-38657. , 9 p. (2010)PDF

Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5, FASEB J. ,24 : 11 pp. 4480-4490. , 11 p. (2010)

Emerging complex pathways of the actomyosin powerstroke, Trends Biochem Sci.,35 : 12 pp. 684-690. , 7 p. (2010)PDF

Streamlined determination of processive run length and mechanochemical coupling of nucleic acid motor activities., Nucleic Acids Res,38 : 7 Paper: e102 (2010)PDF

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA, Nucleic Acid Res,38 : 13 pp. 4404-4414. , 11 p. (2010)PDF

Diversity of structural behavior in vertebrate conventional myosins complexed with actin, J Mol Biol,369 : 1 pp. 249-264. , 16 p. (2007)PDF

Human myosin Vc is a low duty ratio, nonprocessive molecular motor, J Biol Chem,283 : 13 pp. 8527-8537. , 11 p. (2008)

Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor, Structure,15 : 5 pp. 553-564. , 12 p. (2007)PDF

Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme, J Biol Chem,282 : 46 pp. 33572-33582. , 11 p. (2007)

Selective perturbation of the Myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release, J Biol Chem,282 : 24 pp. 17658-17664. , 7 p. (2007)

Load-dependent mechanism of nonmuscle myosin 2, Proc Natl Acad Sci U S A,104 : 24 pp. 9994-9999. , 6 p. (2007)PDF

Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus, Biophys J,91 : 12 pp. 4605-4610. , 6 p. (2006)PDF

Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue, Biochem,45 : 43 pp. 13035-13045. , 11 p. (2006)PDF

Myosin VIIB from Drosophila is a high duty ratio motor, J Biol Chem,280 : 37 pp. 32061-32068. , 8 p. (2005)

Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family, J Biol Chem,280 : 34 pp. 30594-30603. , 10 p. (2005)

Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400, J Biol Chem,280 : 29 pp. 26974-26983. , 10 p. (2005)PDF

Mechanism of action of the membrane motor myosin X, J Biol Chem,280 : 15 pp. 15071-15083. , 13 p. (2005)

Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C, J Biol Chem,280 : 24 pp. 22769-22775. , 7 p. (2005)

Dimerized Drosophila myosin VIIa: a processive motor, Proc Natl Acad Sci U S A,103 : 15 pp. 5746-5751. , 6 p. (2006)PDF

Mechanism of blebbistatin inhibition of myosin II, J Biol Chem,279 : 34 pp. 35557-35563. , 7 p. (2004)PDF

Engineering lysine reactivity as a conformational sensor in the Dictyostelium myosin II motor domain, J Muscle Res Cell Motil,25 : 1 pp. 95-102. , 8 p. (2004)

Two-headed binding of the unphosphorylated nonmuscle heavy meromyosin-ADP complex to actin, Biochemistry,43 : 14 pp. 4219-4226. , 8 p. (2004)PDF

Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance, J Biol Chem,278 : 30 pp. 27439-27448. , 10 p. (2003)PDF

Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform, J Biol Chem,278 : 40 pp. 38132-38140. , 9 p. (2003)PDF

Myosin cleft movement and its coupling to actomyosin dissociation, Nat Struct Biol,10 : 10 pp. 831-835. , 5 p. (2003)

Engineering Dictyostelium discoideum myosin II for the introduction of site-specific fluorescence probes, J Muscle Res Cell Motil,23 : 7-8 pp. 673-683. , 11 p. (2002)PDF

Analysis of nucleotide binding to Dictyostelium myosin II motor domains containing a single tryptophan near the active site, J Biol Chem,277 : 32 pp. 28459-28467. , 9 p. (2002)PDF

Kinetic resolution of a conformational transition and the ATP hydrolysis step using relaxation methods with a Dictyostelium myosin II mutant containing a single tryptophan residue, Biochemistry,40 : 42 pp. 12727-12737. , 11 p. (2001)PDF

The dynamics of the relay loop tryptophan residue in the Dictyostelium myosin motor domain and the origin of spectroscopic signals, J Biol Chem,276 : 22 pp. 19483-19490. , 8 p. (2001)PDF

Lágymányosi Csetepaté: Az emberiség ára: enni vagy lenni?, Vitaműsor az ELTE TTK-n, 2023. december 13.

Az emberiség ára: enni vagy lenni?, Qubit, 2023. december 8.

Lágymányosi Csetepaté: Eljön a dizájner bébik kora?, Vitaműsor at ELTE TTK-n, 2022. november 16.

A társadalom még nem készült fel a génszerkesztett gyerekekre, Qubit, 2022. november 18.

Magyar kutatók eredménye is segíthet a szuperbaktériumok ellen, MTA honlap, 2017. március 6.

Motorfehérjék a DNS-szálakon, Élet és Tudomány, 2014/1. (interjú)Teljes cikk

Hibák a DNS-ben, ELTE honlap, 2012. február 22. (interjú)

Osztrák akadémiai elismerés a Lendület program kutatójának, MTA honlap, 2012. január 25.

A motorenzimek szerepe a rákkutatásban, MTA honlap, 2011. július 5.

Kovács Mihály Lendület-ösztöndíjas kutató, MTA honlap, interjú, 2011. július 5.

Lágymányosi Csetepaté: Az emberiség ára: enni vagy lenni?, Vitaműsor az ELTE TTK-n, 2023. december 13.

Az emberiség ára: enni vagy lenni?, Qubit, 2023. december 8.

Lágymányosi Csetepaté: Eljön a dizájner bébik kora?, Vitaműsor at ELTE TTK-n, 2022. november 16.

A társadalom még nem készült fel a génszerkesztett gyerekekre, Qubit, 2022. november 18.

DNS-hibajavítás megkettőződéskor, Természet Világa, 2013, 144/5.Teljes cikk

A kulcstól a bulldózerig: szárnyas hélix domének funkcionális adaptációja DNS-kötő fehérjékben, Biokémia, 2012 júniusTeljes cikk

Motorenzimek működési alapelvei és egyedi finomhangolása, Biokémia, 2010 júniusTeljes cikk